Intermittent Fasting Modulation of the Diabetic Syndrome in Streptozotocin-Injected Rats

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Intermittent Fasting Modulation of the Diabetic Syndrome in Streptozotocin-Injected Rats

This study investigates the effects of intermittent overnight fasting in streptozotocin-induced diabetic rats (STZ rats). Over 30 days, groups of 5-6 control or STZ rats were allowed free food access, starved overnight, or exposed to a restricted food supply comparable to that ingested by the intermittently fasting animals. Intermittent fasting improved glucose tolerance, increased plasma insul...

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Intermittent Fasting Modulation of the Diabetic Syndrome in Streptozoto- cin-Injected Rats: Post-Mortem Investigations

Intermittent fasting was previously reported to exert beneficial effects in sand rats, an animal model of diabetes. The present report complements recent comparable findings recorded in streptozotocin-induced diabetic rats (STZ rats). Intermittent fasting minimized the increase in pancreatic, hepatic and renal weight otherwise observed in the STZ rats. The glycogen content of the liver was high...

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Intermittent fasting modulation of the diabetic syndrome in sand rats. II. In vivo investigations.

This study deals with the effects of daily intermittent fasting for 15 h upon the development of diabetes in sand rats exposed to a hypercaloric diet. The same pattern of daily intermittent fasting was imposed on sand rats maintained on a purely vegetal diet (control animals). Over the last 30 days of the present experiments, non-fasting animals gained weight, whilst intermittently fasting sand...

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Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations.

The present report concerns several post-mortem variables examined in sand rats that were either maintained on a vegetal diet (control animals) or exposed first during a 20-day transition period to a mixed diet consisting of a fixed amount of a hypercaloric food and decreasing amounts of the vegetal food and then to a 30-day experimental period of exposure to the hypercaloric food. During the l...

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ژورنال

عنوان ژورنال: International Journal of Endocrinology

سال: 2012

ISSN: 1687-8337,1687-8345

DOI: 10.1155/2012/962012